Staphylococcus aureus mediastinitis and sternal osteomyelitis following median sternotomy in a rat model
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چکیده
منابع مشابه
Staphylococcus aureus mediastinitis and sternal osteomyelitis following median sternotomy in a rat model.
OBJECTIVES Median sternotomy (MS) wound infections are severe complications causing high morbidity and mortality after cardiac surgery. We aimed to develop a new Staphylococcus aureus mediastinitis and sternal osteomyelitis model in rats that can be used to evaluate the efficacy of new antimicrobial treatments. METHODS AND RESULTS A complete MS wound was induced in anaesthetized rats. S. aure...
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BACKGROUND Deep sternal wound complications are uncommon after cardiac surgery. They comprise sternal dehiscence, deep sternal wound infections and mediastinitis, which will be treated as varying expressions of a singular pathology for reasons explained in the text. METHODOLOGY AND REVIEW This article reviews the definition, prevalence, risk factors, prevention, diagnosis, microbiology and ma...
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OBJECTIVE In the post-sternotomy mediastinitis patients, Staphylococcus aureus is the pathogenic microorganism encountered most often. In our study, we aimed to determine the efficacy of antibiotic treatment with vancomycin and tigecycline, alone or in combination with hyperbaric oxygen treatment, on bacterial elimination in experimental S. aureus mediastinitis. METHODS Forty-nine adult femal...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2008
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/dkn378